The key target of milk thistle supplementation has been the reduction of liver disease. Silymarin is effective in managing the impact of various toxins which cause liver damage. These would include alcohol, chemotherapy agents, and paracetamol.
Allen Nutraceutical Product
- Supports Healthy Liver Function
- Liver Detoxification & Waste Elimination
- Powerful Antioxidant
Primary Health Benefit:
Liver Disease:Â The key target of milk thistle supplementation has been the reduction of liver disease. Silymarin is effective in managing the impact of various toxins which cause liver damage. These would include alcohol, chemotherapy agents, and paracetamol.
In clinical studies, the use of silymarin has been shown to facilitate protection against liver damage, and one of the primary attributes of silymarin has been identified are its antioxidant functions.
Additionally, milk thistle has further influences in the regenerative capacity of the liver; assists in the information of new liver cells and provides further cellular protection by stabilizingÂ liver cell membranes to prevent toxins moving into the cells.
The larger impact of these physiologicalÂ benefits is the impediment of fibrosis and cirrhosis due to excessive liver inflammation ( commonly seen in alcoholism); improved immune function and response to liver damage.
How It Works
Milk thistle is a tall herb which grows to approximately 10 feet high in various corners of the globe, including Southern and western Europe, Southern America and the Eastern United States. It characteristically has large purplish flowers and small hard seed-like fruits (called achenes) which are the source of its medicinal properties.
Achenes contain approximatelyÂ 1-4% of the flavonoid mixture, silymarin. It is these Achenes which are used to create the concentrated silymarin extract that has higher compounds which have various regulatory effects on our metabolism. Silymarin contributes to our oxidative protection in various ways.
- Directly scavenging free radicals ( and in essence removing free radicals from the cellular environment)
- By inhibiting enzymes which allow free radical formation
- By maintaining the electron transport chain during stress conditions
- By activatingÂ antioxidant enzymes and transcription factors which are responsible for the synthesis of protective molecules (such as thitedoxin and HSP)
- By reducing the inflammatory response through inhibition of NF-KB pathways (Which is a protein complex which regulates the immune response).