EL D3 provides high potency pharmaceutical grade vitamin D3. Each 1gm sachet contains an optimum level of 60,000 IU of vitamin D3. Vitamin D plays a truly remarkable role in the body and is essential for all round good health.
EL D3 provides high potency pharmaceutical grade vitamin D3. Each 1gm sachet contains an optimum level of 60,000 IU of vitamin D3. Vitamin D plays a truly remarkable role in the body and is essential for all round good health. It is not only vital for strong bones, but is now known for its role in the immune system, cardio-vascular health, cell division and normal muscle function.
EL D3's high strength vitamin D3 helps maintain all round good health including, mood, normal functioning of the Immune system, maintenance of normal bones and teeth, Cardio-vascular function.
Synthesised in the skin via exposure to sunlight, vitamin D is often associated with the term 'the sunshine vitamin'. As we age, we are thought to be more at risk of vitamin D deficiency because our skin's ability to convert vitamin D into its active form decreases. Vitamin D is synthesized by the body on exposure to sunlight, however many people are now following health advice to avoid too much sun exposure, which reduces vitamin D levels in the body.Â
HOW IT WORKS :
Vitamin D has several important functions. Perhaps the most vital are regulating the absorption of calcium and phosphorous, and facilitating normal immune system function.
The first step involved in the activation of vitamin D3 is a 25-hydroxylation which is catalysed by the 25-hydroxylase in the liver and then by other enzymes. The mitochondrial sterol 27-hydroxylase catalyses the first reaction in the oxidation of the side chain of sterol intermediates. The active form of vitamin D3 (calcitriol) binds to intracellular receptors that then function as transcription factors to modulate gene expression. Like the receptors for other steroid hormones and thyroid hormones, the vitamin D receptor has hormone-binding and DNA-binding domains. The vitamin D receptor forms a complex with another intracellular receptor, the retinoid-X receptor, and that heterodimer is what binds to DNA. In most cases studied, the effect is to activate transcription, but situations are also known in which vitamin D suppresses transcription. Calcitriol increases the serum calcium concentrations by: increasing GI absorption of phosphorus and calcium, increasing osteoclastic resorption, and increasing distal renal tubular reabsorption of calcium. Calcitriol appears to promote intestinal absorption of calcium through binding to the vitamin D receptor in the mucosal cytoplasm of the intestine. Subsequently, calcium is absorbed through formation of a calcium-binding protein. Vitamin D3 is a steroid hormone that has long been known for its important role in regulating body levels of calcium and phosphorus, in mineralization of bone.